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Seventeen countries have announced plans to phase out sales of new gasoline-powered passenger vehicles. In the US, in the absence of a federal policy, state-level vehicle electrification mandates are a promising mechanism to achieve quantum leaps in EV sales volumes, and a critical step on the path to nationwide vehicle electrification. Federal preemption concerns have hindered introduction of state-level vehicle electrification mandates. However, recent Supreme Court precedent has opened a path for state mandates to withstand preemption challenges, provided the legislation is based on state interests other than vehicle emissions reduction and improved fuel economy standards.

The fight against antibiotic resistance must be strengthened. We propose actions that U.S. government agencies and private sector entities can take to build a more comprehensive effort. These actions can increase the viability of investing in new antibiotics, ensure the quality and stewardship of all antibiotics, and make responses to emerging resistance more informed. Success requires the thoughtful exercise of federal authority and a firm commitment to share data and reward developers for the value generated with new, life-saving antibiotics.